When mixed with saline or lidocaine, hyper-diluted Radiesse is injected superficially under aging skin using a blunt-tip cannula and acts as a bio-stimulating agent rather than a volumizer, which work to improve elasticity and tighten the skin.

The skin rejuvenating effects from this treatment are pronounced and visible, with collagen and elastin production starting as early as 4 weeks after injection. This results in long term skin tightening with progressive natural dermal thickening. This means that fine lines, crepiness, and skin laxity are reduced. The tone, elasticity and pliability of skin is markedly improved.